5Z79
Crystal Structure Analysis of the HPPK-DHPS in complex with substrates
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase, putative | polymer | 717 | 82484.2 | 6 | UniProt (A0A1K9YMY7) Pfam (PF01288) Pfam (PF00809) UniProt (by SIFTS) (A5JZS1) | Plasmodium vivax | |
| 2 | CA, G, L, O, T... (F, A, B, C, D...) | 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE | non-polymer | 353.1 | 6 | Chemie (HH2) | |||
| 3 | H, P (A, C) | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 2 | Chemie (APC) | |||
| 4 | DA, I, N, Q, V... (F, A, B, C, D...) | 4-AMINOBENZOIC ACID | non-polymer | 137.1 | 6 | Chemie (PAB) | |||
| 5 | AA, J, R, W (E, A, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | BA, K, S, X (E, A, C, D) | PTERINE | non-polymer | 163.1 | 4 | Chemie (PE0) | |||
| 7 | M, U (B, D) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 2 | Chemie (5AD) | |||
| 8 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 717 (UniProt: A0A1K9YMY7)
| PDB | External Database | Details |
|---|---|---|
| Ala 383 | Gly 383 | see sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 494905.5 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5204.2 | |
| All* | Total formula weight | 500109.7 |
