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5Z3N

Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base 5fC pair with dA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase I, thermostablepolymer53960865.91UniProt (P19821)
Pfam (PF09281)
Pfam (PF00476)
Thermus aquaticusTaq polymerase 1
2B
(B)
DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3')polymer123617.41synthetic construct
3C
(C)
DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(5FC)P*GP*GP*TP*C)-3')polymer164937.21synthetic construct
4D, E, K
(A, B)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5F
(A)
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (DGT)
6G, H, I, J, L
(A, C)
GLYCEROLnon-polymer92.15Chemie (GOL)
7M, N, O
(A, B, C)
waterwater18.0498Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight69420.4
Non-Polymers*Number of molecules9
Total formula weight1040.6
All*Total formula weight70461.0
*Water molecules are not included.

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PDB entries from 2025-07-30

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