5Z12
A structure of FXR/RXR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, D) | Bile acid receptor | polymer | 228 | 26673.7 | 2 | UniProt (Q96RI1) Pfam (PF00104) | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
| 2 | B, G (C, B) | Retinoic acid receptor RXR-alpha | polymer | 231 | 25897.0 | 2 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 3 | C, H (F, I) | Peptide from Nuclear receptor coactivator 2 | polymer | 9 | 1161.4 | 2 | UniProt (by SIFTS) (Q15596) | Homo sapiens | |
| 4 | D, F (J, H) | Peptide from Nuclear receptor coactivator 2 | polymer | 6 | 807.0 | 2 | UniProt (by SIFTS) (Q15596) | Homo sapiens | |
| 5 | I, K (A, D) | 1-methylethyl 3-[(3,4-difluorophenyl)carbonyl]-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate | non-polymer | 438.5 | 2 | Chemie (33Y) | |||
| 6 | J, L (C, B) | (9cis)-retinoic acid | non-polymer | 300.4 | 2 | Chemie (9CR) | |||
| 7 | M, N, O, P (A, C, D, B) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 109078.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1477.8 | |
| All* | Total formula weight | 110556.1 |
