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5YYA

Crystal structure of Tandem Tudor Domain of human UHRF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase UHRF1polymer16419213.31UniProt (Q96T88)
Pfam (PF12148)
Homo sapiens (Human)Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,hNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1
2B, C, D
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
3E
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4F
(A)
waterwater18.0244Chemie (HOH)
Sequence modifications
A: 123 - 285 (UniProt: Q96T88)
PDBExternal DatabaseDetails
Ser 122-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19213.3
Non-Polymers*Number of molecules4
Total formula weight282.3
All*Total formula weight19495.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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