5YX1
Crystal structure of hematopoietic prostaglandin D synthase in complex with U004
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Hematopoietic prostaglandin D synthase | polymer | 198 | 23239.6 | 4 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) | Homo sapiens (Human) | H-PGDS,GST class-sigma,Glutathione S-transferase,Glutathione-dependent PGD synthase,Glutathione-requiring prostaglandin D synthase,Prostaglandin-H2 D-isomerase |
| 2 | E, J (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | F, G, K, M (A, B, C, D) | GLUTATHIONE | non-polymer | 307.3 | 4 | Chemie (GSH) | |||
| 4 | H, L, N (B, C, D) | ethyl 4-[(8R)-3,8-dimethyl-4-oxo-4,6,7,8,9,10-hexahydrothieno[2',3':4,5]pyrimido[1,2-a]azepin-2-yl]carbamoylpiperazine-1-carboxylate | non-polymer | 447.6 | 3 | Chemie (UX4) | |||
| 5 | I, O (B, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 895 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92958.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2804.7 | |
| All* | Total formula weight | 95763.3 |
