5YWX
Crystal structure of hematopoietic prostaglandin D synthase in complex with F092
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Hematopoietic prostaglandin D synthase | polymer | 198 | 23239.6 | 4 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) | Homo sapiens (Human) | H-PGDS,GST class-sigma,Glutathione S-transferase,Glutathione-dependent PGD synthase,Glutathione-requiring prostaglandin D synthase,Prostaglandin-H2 D-isomerase |
| 2 | E, J, M, O (A, B, C, D) | GLUTATHIONE | non-polymer | 307.3 | 4 | Chemie (GSH) | |||
| 3 | F, K, N, P (A, B, C, D) | N-[4-(2-oxopyrrolidin-1-yl)phenyl]-2-(pyridin-2-yl)pyrimidine-5-carboxamide | non-polymer | 359.4 | 4 | Chemie (93C) | |||
| 4 | G, H, Q (A, D) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | I, L (B, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | R, S, T, U (A, B, C, D) | water | water | 18.0 | 583 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92958.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2991.7 | |
| All* | Total formula weight | 95950.3 |
