5YVU
Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Genome polyprotein | polymer | 627 | 70044.8 | 1 | UniProt (F8TEL4) Pfam (PF00949) Pfam (PF07652) Pfam (PF20907) In PDB | Dengue virus 4 | |
2 | A | Genome polyprotein | polymer | 55 | 5964.5 | 1 | UniProt (F8TEL4) Pfam (PF01002) In PDB | Dengue virus 4 | |
3 | I | Pancreatic trypsin inhibitor | polymer | 55 | 6342.4 | 1 | UniProt (P00974) Pfam (PF00014) In PDB | Bos taurus (Bovine) | Aprotinin,Basic protease inhibitor,BPTI |
4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
B: 1 - 618 (UniProt: F8TEL4)
A: 49 - 95 (UniProt: F8TEL4)
PDB | External Database | Details |
---|---|---|
Gly -8 | - | expression tag |
Gly -7 | - | expression tag |
Gly -6 | - | expression tag |
Gly -5 | - | expression tag |
Ser -4 | - | expression tag |
Gly -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
Gly 0 | - | expression tag |
Ala 135 | Ser 1609 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Phe 41 | - | expression tag |
Lys 42 | - | expression tag |
Pro 43 | - | expression tag |
Gly 44 | - | expression tag |
Thr 45 | - | expression tag |
Ser 46 | - | expression tag |
Gly 47 | - | expression tag |
Ser 48 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 82351.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 82443.7 |