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5YTH

Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base M-fC pair with dG

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase I, thermostablepolymer53960865.91UniProt (P19821)Thermus aquaticusTaq polymerase 1
2B
(B)
DNA (5'-D(*GP*AP*CP*CP*GP*CP*GP*GP*CP*GP*CP*(DOC))-3')polymer123633.41synthetic construct
3C
(C)
DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(92F)P*GP*GP*TP*C)-3')polymer164985.21synthetic construct
4D
(A)
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (DGT)
PubChem (177678918)
PubChem (136110594)
PubChem (135398599)
PubChem (135402022)
PubChem (135566345)
PubChem (136254580)
PubChem (136633653)
PubChem (136828797)
PubChem (136828798)
PubChem (137226754)
PubChem (137257907)
PubChem (171699498)
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
PubChem (888)
6G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
PubChem (753)
7H, I, J
(A, B, C)
waterwater18.075Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight69484.5
Non-Polymers*Number of molecules4
Total formula weight647.9
All*Total formula weight70132.4
*Water molecules are not included.

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PDB entries from 2026-04-08

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