5YST
RanM189D in complex with RanBP1-CRM1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTP-binding nuclear protein Ran | polymer | 216 | 24440.0 | 1 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (Human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 2 | B (B) | Ran-specific GTPase-activating protein 1 | polymer | 139 | 16249.6 | 1 | UniProt (P41920) Pfam (PF00638) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Chromosome stability protein 20,Perinuclear array-localized protein,Ran-binding protein 1,RANBP1 |
| 3 | C (C) | Exportin-1,Exportin-1 | polymer | 1017 | 116682.1 | 1 | UniProt (P30822) Pfam (PF03810) Pfam (PF08389) Pfam (PF18777) Pfam (PF18784) Pfam (PF18787) Pfam (PF08767) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Chromosome region maintenance protein 1,Karyopherin-124,Chromosome region maintenance protein 1,Karyopherin-124 |
| 4 | D (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 5 | E, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | H, J, K, L, M... (A, C) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 8 | I, O, P, Q, R (C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 9 | S, T, U (A, B, C) | water | water | 18.0 | 636 | Chemie (HOH) |
Sequence modifications
A: 1 - 216 (UniProt: P62826)
C: 1 - 376 (UniProt: P30822)
C: 414 - 1052 (UniProt: P30822)
| PDB | External Database | Details |
|---|---|---|
| Asp 189 | Met 189 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 537 | Asp 537 | engineered mutation |
| Cys 539 | Thr 539 | engineered mutation |
| Glu 540 | Val 540 | engineered mutation |
| Gln 541 | Lys 541 | engineered mutation |
| Cys 1022 | Tyr 1022 | see sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 157371.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1307.0 | |
| All* | Total formula weight | 158678.7 |
