5YPR

Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Disks large homolog 4	polymer	318	36835.2	1	UniProt (P31016) Pfam (PF00018) Pfam (PF00625) In PDB	Rattus norvegicus (Rat)	Postsynaptic density protein 95,PSD-95,Synapse-associated protein 90,SAP90
2	B	Synthesized GK inhibitor	polymer	16	2056.3	1		synthetic construct
3		water	water		18.0	42	Chemie (HOH)

Sequence modifications

A: 426 - 721 (UniProt: P31016)

PDB	External Database	Details
Met 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag
His 410	-	expression tag
Ser 411	-	expression tag
Ser 412	-	expression tag
Gly 413	-	expression tag
Leu 414	-	expression tag
Glu 415	-	expression tag
Val 416	-	expression tag
Leu 417	-	expression tag
Phe 418	-	expression tag
Gln 419	-	expression tag
Gly 420	-	expression tag
Pro 421	-	expression tag
Gly 422	-	expression tag
Ser 423	-	expression tag
Glu 424	-	expression tag
Phe 425	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38891.5
All*	Total formula weight	38891.5

*Water molecules are not included.