5YP2
Crystal structure of dipeptidyl peptidase IV (DPP IV) with DPP4 inhibitor from Pseudoxanthomonas mexicana WO24
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dipeptidyl aminopeptidase 4 | polymer | 745 | 82375.5 | 2 | UniProt (Q6F3I7) Pfam (PF00930) Pfam (PF00326) | Pseudoxanthomonas mexicana (Pseudomonas sp. WO24) | Dipeptidyl aminopeptidase IV,DAP IV |
| 2 | C, F (A, B) | (2S,5R)-1-[2-[[1-(hydroxymethyl)cyclopentyl]amino]ethanoyl]pyrrolidine-2,5-dicarbonitrile | non-polymer | 276.3 | 2 | Chemie (8YC) | |||
| 3 | D, E, G (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 700 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 745 (UniProt: Q6F3I7)
| PDB | External Database | Details |
|---|---|---|
| Ile 12 | Met 12 | see sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 164751.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 829.0 | |
| All* | Total formula weight | 165580.0 |
