5YLT
Crystal structure of SET7/9 in complex with a cyproheptadine derivative
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone-lysine N-methyltransferase SETD7 | polymer | 263 | 29083.2 | 1 | UniProt (Q8WTS6) Pfam (PF02493) Pfam (PF00856) In PDB | Homo sapiens (Human) | Histone H3-K4 methyltransferase SETD7,H3-K4-HMTase SETD7,Lysine N-methyltransferase 7,SET domain-containing protein 7,SET7/9 |
2 | A | SINEFUNGIN | non-polymer | 381.4 | 1 | Chemie (SFG) | |||
3 | A | 2-(1-methylpiperidin-4-ylidene)tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-6-ol | non-polymer | 303.4 | 1 | Chemie (C7N) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 111 - 366 (UniProt: Q8WTS6)
PDB | External Database | Details |
---|---|---|
Gly 104 | - | expression tag |
Ser 105 | - | expression tag |
Ser 106 | - | expression tag |
Gly 107 | - | expression tag |
Ser 108 | - | expression tag |
Ser 109 | - | expression tag |
Gly 110 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29083.2 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 961.1 | |
All* | Total formula weight | 30044.3 |