5YIB
Crystal Structure of KNI-10743 bound Plasmepsin II (PMII) from Plasmodium falciparum
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Plasmepsin II | polymer | 328 | 36856.6 | 1 | UniProt (Q8I6V3) Pfam (PF00026) | Plasmodium falciparum (isolate 3D7) | |
| 2 | B (A) | (4R)-3-[(2S,3S)-3-[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2,6-dimethyl-phenoxy]ethanoylamino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-N-[(1S,2R)-2-oxidanyl-2,3-dihydro-1H-inden-1-yl]-1,3-thiazolidine-4-carboxamide | non-polymer | 731.9 | 1 | Chemie (8VC) | |||
| 3 | C, D, E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | H, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | J (A) | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | non-polymer | 614.9 | 1 | Chemie (CPS) | |||
| 6 | K (A) | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36856.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1931.4 | |
| All* | Total formula weight | 38788.1 |
