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5YG4

Plasmodium vivax SHMT bound with PLP-glycine and S-GS849

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Serine hydroxymethyltransferasepolymer44249249.23UniProt (A0A1G4H5I1)
Pfam (PF00464)
Plasmodium vivax
2D, H, K
(A, B, C)
N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]non-polymer306.23Chemie (PLG)
3E, I, L
(A, B, C)
2-[1-[(3~{S})-6'-azanyl-5'-cyano-7-fluoranyl-2,2,3'-trimethyl-spiro[1~{H}-indene-3,4'-2~{H}-pyrano[2,3-c]pyrazole]-5-yl]piperidin-4-yl]ethanoic acidnon-polymer465.53Chemie (8UF)
4F, M
(A, C)
CHLORIDE IONnon-polymer35.52Chemie (CL)
5G, J, N
(A, B, C)
GLYCEROLnon-polymer92.13Chemie (GOL)
6O, P, Q
(A, B, C)
waterwater18.0370Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight147747.5
Non-Polymers*Number of molecules11
Total formula weight2662.4
All*Total formula weight150409.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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