5YCN
Human PPARgamma ligand binding domain complexed with Lobeglitazone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 283 | 32280.3 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 16 | 1905.2 | 1 | UniProt (Q15788) | Homo sapiens | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
| 3 | C (A) | (5S)-5-[[4-[2-[[6-(4-methoxyphenoxy)pyrimidin-4-yl]-methyl-amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione | non-polymer | 480.5 | 1 | Chemie (8LX) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34185.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 480.5 | |
| All* | Total formula weight | 34666.1 |
