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5YC6

The crystal structure of uPA in complex with 4-Bromobenzylamirne at pH4.6

Replaces:  4JNI
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(U)
Urokinase-type plasminogen activatorpolymer24627715.61UniProt (P00749)
Pfam (PF00089)
Homo sapiens (Human)uPA
2B
(U)
1-(4-BROMOPHENYL)METHANAMINEnon-polymer186.01Chemie (PZH)
3C
(U)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E
(U)
TRIETHYLENE GLYCOLnon-polymer150.22Chemie (PGE)
5F
(U)
waterwater18.0214Chemie (HOH)
Sequence modifications
U: 16 - 243 (UniProt: P00749)
PDBExternal DatabaseDetails
Ala 122Cys 299conflict
Gln 145Asn 322conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight27715.6
Non-Polymers*Number of molecules4
Total formula weight582.5
All*Total formula weight28298.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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