5YBG
Crystal structure of the GluA2o LBD in complex with glutamate and LY451395
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Glutamate receptor 2,Glutamate receptor 2 | polymer | 263 | 29337.8 | 6 | UniProt (P42262) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (Human) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2 |
| 2 | EA, G, M, O, U... (F, A, B, C, D...) | GLUTAMIC ACID | non-polymer | 147.1 | 6 | Chemie (GLU) | |||
| 3 | AA, H, P (E, A, C) | N-[(2R)-2-[4-[4-[2-(methylsulfonylamino)ethyl]phenyl]phenyl]propyl]propane-2-sulfonamide | non-polymer | 438.6 | 3 | Chemie (8SO) | |||
| 4 | BA, FA, I, L, N... (E, F, A, B, C...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 5 | CA, J, S, T, X (E, A, C, D) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 6 | DA, K (E, A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | GA, HA, IA, JA, KA... (A, B, C, D, E...) | water | water | 18.0 | 1242 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 413 - 527 (UniProt: P42262)
A, B, C, D, E, F: 653 - 796 (UniProt: P42262)
| PDB | External Database | Details |
|---|---|---|
| Gly 411 | - | expression tag |
| Ser 412 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 641 | - | linker |
| Thr 642 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 176027.0 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3332.1 | |
| All* | Total formula weight | 179359.1 |
