5YBG

Crystal structure of the GluA2o LBD in complex with glutamate and LY451395

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Glutamate receptor 2,Glutamate receptor 2	polymer	263	29337.8	6	UniProt (P42262) Pfam (PF10613) Pfam (PF00060) In PDB	Homo sapiens (Human)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2
2	F, A, B, C, D...	GLUTAMIC ACID	non-polymer		147.1	6	Chemie (GLU)
3	E, A, C	N-[(2R)-2-[4-[4-[2-(methylsulfonylamino)ethyl]phenyl]phenyl]propyl]propane-2-sulfonamide	non-polymer		438.6	3	Chemie (8SO)
4	E, F, A, B, C...	ZINC ION	non-polymer		65.4	10	Chemie (ZN)
5	E, A, C, D	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)
6	E, A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7		water	water		18.0	1242	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 413 - 527 (UniProt: P42262)

PDB	External Database	Details
Gly 411	-	expression tag
Ser 412	-	expression tag

A, B, C, D, E, F: 653 - 796 (UniProt: P42262)

PDB	External Database	Details
Gly 641	-	linker
Thr 642	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	176027.0
Non-Polymers*	Number of molecules	26
	Total formula weight	3332.1
All*	Total formula weight	179359.1

*Water molecules are not included.