5YAW
Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 150 | 17441.0 | 1 | UniProt (O43924) Pfam (PF05351) | Homo sapiens (Human) | GMP-PDE delta,Protein p17 |
| 2 | B (B) | 3-[(4-methoxyphenyl)methylsulfanyl]-5-(2-methylpropyl)-4-(phenylmethyl)-1,2,4-triazole | non-polymer | 367.5 | 1 | Chemie (8SL) | |||
| 3 | C (B) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17441.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 367.5 | |
| All* | Total formula weight | 17808.5 |
