5YAW
Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0005095 | molecular_function | GTPase inhibitor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005929 | cellular_component | cilium |
| B | 0007601 | biological_process | visual perception |
| B | 0016020 | cellular_component | membrane |
| B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| B | 0031267 | molecular_function | small GTPase binding |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0042995 | cellular_component | cell projection |
| B | 0050953 | biological_process | sensory perception of light stimulus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue 8SL B 201 |
| Chain | Residue |
| B | MET20 |
| B | LEU38 |
| B | SER39 |
| B | ARG61 |
| B | LEU76 |
| B | GLN78 |
| B | ILE109 |
| B | THR131 |
| B | PHE133 |
