5Y94
Crystal Structure Analysis of the BRD4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain-containing protein 4 | polymer | 141 | 16767.3 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
2 | A | 5-bromanyl-2-methoxy-N-[3-methyl-6-(methylamino)-1,2-benzoxazol-5-yl]benzenesulfonamide | non-polymer | 426.3 | 1 | Chemie (8QC) | |||
3 | A | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 44 - 168 (UniProt: O60885)
PDB | External Database | Details |
---|---|---|
Met 28 | - | expression tag |
Lys 29 | - | expression tag |
Lys 30 | - | expression tag |
Gly 31 | - | expression tag |
His 32 | - | expression tag |
His 33 | - | expression tag |
His 34 | - | expression tag |
His 35 | - | expression tag |
His 36 | - | expression tag |
His 37 | - | expression tag |
Leu 38 | - | expression tag |
Val 39 | - | expression tag |
Pro 40 | - | expression tag |
Arg 41 | - | expression tag |
Gly 42 | - | expression tag |
Ser 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16767.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 665.4 | |
All* | Total formula weight | 17432.7 |