5Y90
MAP2K7 mutant -C218S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity mitogen-activated protein kinase kinase 7 | polymer | 323 | 36851.6 | 1 | UniProt (O14733) Pfam (PF00069) | Homo sapiens (Human) | MAPKK 7,JNK-activating kinase 2,MAPK/ERK kinase 7,MEK 7,Stress-activated protein kinase kinase 4,SAPKK4,c-Jun N-terminal kinase kinase 2,JNKK 2 |
| 2 | B, C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | F (A) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A: 119 - 435 (UniProt: O14733)
| PDB | External Database | Details |
|---|---|---|
| Ser 218 | Cys 202 | engineered mutation |
| His 436 | - | expression tag |
| His 437 | - | expression tag |
| His 438 | - | expression tag |
| His 439 | - | expression tag |
| His 440 | - | expression tag |
| His 441 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36851.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 37220.0 |
