5Y8Z
Crystal Structure Analysis of the BRD4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 141 | 16767.3 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B (A) | 5-bromanyl-N-(3,6-dimethyl-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide | non-polymer | 411.3 | 1 | Chemie (8Q3) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E, F (A) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 5 | G (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | H (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | I (A) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Lys 30 | - | expression tag |
| Gly 31 | - | expression tag |
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| His 37 | - | expression tag |
| Leu 38 | - | expression tag |
| Val 39 | - | expression tag |
| Pro 40 | - | expression tag |
| Arg 41 | - | expression tag |
| Gly 42 | - | expression tag |
| Ser 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16767.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 774.5 | |
| All* | Total formula weight | 17541.8 |
