5Y7Z
Complex structure of cyclin G-associated kinase with gefitinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cyclin-G-associated kinase | polymer | 313 | 35657.8 | 2 | UniProt (O14976) Pfam (PF00069) In PDB | Homo sapiens (Human) | |
| 2 | D, C | NANOBODY | polymer | 148 | 16189.7 | 2 | Lama glama | ||
| 3 | A, B | Gefitinib | non-polymer | 446.9 | 2 | Chemie (IRE) | |||
| 4 | A, B, D, C | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 335 (UniProt: O14976)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 103695.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1374.1 | |
| All* | Total formula weight | 105069.1 |
