5Y7N
Crystal structure of AKR1B10 in complex with NADP+ and Androst-4-ene-3-beta-6-alpha-diol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Aldo-keto reductase family 1 member B10 | polymer | 316 | 36071.5 | 1 | UniProt (O60218) Pfam (PF00248) In PDB | Homo sapiens (Human) | ARL-1,Aldose reductase-like,Aldose reductase-related protein,hARP,Small intestine reductase,SI reductase |
2 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
3 | A | (3S,6S,8S,9S,10R,13S,14R)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol | non-polymer | 290.4 | 1 | Chemie (8QL) | |||
4 | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36071.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1033.8 | |
All* | Total formula weight | 37105.4 |