5Y65

Phosphoglycerate mutase 1 complexed with a small molecule inhibitor KH2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Phosphoglycerate mutase 1	polymer	262	29917.1	1	UniProt (P18669) Pfam (PF00300) In PDB	Homo sapiens (Human)	BPG-dependent PGAM 1,Phosphoglycerate mutase isozyme B,PGAM-B
2	C	Phosphoglycerate mutase 1	polymer	262	29996.1	1	UniProt (P18669) Pfam (PF00300) In PDB	Homo sapiens (Human)	BPG-dependent PGAM 1,Phosphoglycerate mutase isozyme B,PGAM-B
3	B	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	C	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
5	C	~{N}-[3,4-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen-2-yl]-4-(dimethylamino)benzenesulfonamide	non-polymer		438.5	1	Chemie (HKB)
6		water	water		18.0	54	Chemie (HOH)

Sequence modifications

B: 1 - 254 (UniProt: P18669)

PDB	External Database	Details
Leu 255	-	expression tag
Glu 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag
His 262	-	expression tag

C: 1 - 254 (UniProt: P18669)

PDB	External Database	Details
Leu 255	-	expression tag
Glu 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag
His 262	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59913.2
Non-Polymers*	Number of molecules	3
	Total formula weight	669.1
All*	Total formula weight	60582.3

*Water molecules are not included.