5Y3K
Crystal structure of horse TLR9 in complex with two DNAs (CpG DNA and GCGCAC DNA)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Toll-like receptor 9 | polymer | 802 | 89427.6 | 2 | UniProt (Q2EEY0) Pfam (PF13516) Pfam (PF00560) Pfam (PF13855) Pfam (PF18837) In PDB | Equus caballus (Horse) | |
2 | C, D | DNA (5'-D(*AP*GP*GP*CP*GP*TP*TP*TP*TP*T)-3') | polymer | 10 | 3066.0 | 2 | synthetic construct | ||
3 | E, F | DNA (5'-D(*GP*CP*GP*CP*AP*C)-3') | polymer | 6 | 1794.2 | 2 | synthetic construct | ||
4 | G, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) | |||
6 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 819 (UniProt: Q2EEY0)
PDB | External Database | Details |
---|---|---|
Arg 22 | - | expression tag |
Ser 23 | - | expression tag |
Pro 24 | - | expression tag |
Trp 25 | - | expression tag |
Glu 818 | Cys 818 | conflict |
Leu 820 | - | expression tag |
Val 821 | - | expression tag |
Pro 822 | - | expression tag |
Arg 823 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 188575.6 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 3318.1 | |
All* | Total formula weight | 192742.5 |