5Y3K
Crystal structure of horse TLR9 in complex with two DNAs (CpG DNA and GCGCAC DNA)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002224 | biological_process | toll-like receptor signaling pathway |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
| B | 0002224 | biological_process | toll-like receptor signaling pathway |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0006955 | biological_process | immune response |
| B | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1582 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | GLN26-ASP817 | |
| B | GLN26-ASP817 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25686612, ECO:0007744|PDB:3WPC |
| Chain | Residue | Details |
| B | TRP47 | |
| B | SER72 | |
| B | LYS95 | |
| B | TYR132 | |
| B | ARG152 | |
| B | TYR179 | |
| B | TYR208 | |
| B | ARG262 | |
| A | TRP47 | |
| A | SER72 | |
| A | LYS95 | |
| A | TYR132 | |
| A | ARG152 | |
| A | TYR179 | |
| A | TYR208 | |
| A | ARG262 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q9NR96 |
| Chain | Residue | Details |
| B | CYS258 | |
| B | CYS265 | |
| A | CYS258 | |
| A | CYS265 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 |
| Chain | Residue | Details |
| A | ASN64 | |
| B | ASN669 | |
| A | ASN129 | |
| A | ASN340 | |
| A | ASN472 | |
| A | ASN669 | |
| B | ASN64 | |
| B | ASN129 | |
| B | ASN340 | |
| B | ASN472 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:25686612, ECO:0007744|PDB:3WPC |
| Chain | Residue | Details |
| B | ASN694 | |
| B | ASN242 | |
| B | ASN309 | |
| B | ASN513 | |
| A | ASN200 | |
| A | ASN242 | |
| A | ASN309 | |
| A | ASN513 | |
| A | ASN694 | |
| B | ASN200 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:25686612, ECO:0007744|PDB:3WPB, ECO:0007744|PDB:3WPC, ECO:0007744|PDB:3WPD |
| Chain | Residue | Details |
| A | ASN210 | |
| A | ASN567 | |
| A | ASN731 | |
| B | ASN210 | |
| B | ASN567 | |
| B | ASN731 |
