5Y39

Crystal structure of Ragulator complex (p18 76-145)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, F (A, F)	Ragulator complex protein LAMTOR1	polymer	70	7966.0	2	UniProt (Q6IAA8)	Homo sapiens (Human)	Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1,Lipid raft adaptor protein p18,Protein associated with DRMs and endosomes,p27Kip1-releasing factor from RhoA,p27RF-Rho
2	B, G (B, G)	Ragulator complex protein LAMTOR2	polymer	125	13517.5	2	UniProt (Q9Y2Q5) Pfam (PF03259)	Homo sapiens (Human)	Endosomal adaptor protein p14,Late endosomal/lysosomal Mp1-interacting protein,Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2,Mitogen-activated protein-binding protein-interacting protein,MAPBP-interacting protein,Roadblock domain-containing protein 3
3	C, H (C, H)	Ragulator complex protein LAMTOR3	polymer	124	13637.7	2	UniProt (Q9UHA4) Pfam (PF08923)	Homo sapiens (Human)	Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3,MEK-binding partner 1,Mp1,Mitogen-activated protein kinase kinase 1-interacting protein 1,Mitogen-activated protein kinase scaffold protein 1
4	D, I (D, I)	Ragulator complex protein LAMTOR4	polymer	101	10941.5	2	UniProt (Q0VGL1)	Homo sapiens (Human)	Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4
5	E, J (E, J)	Ragulator complex protein LAMTOR5	polymer	90	9535.8	2	UniProt (O43504) Pfam (PF16672)	Homo sapiens (Human)	Hepatitis B virus X-interacting protein,HBX-interacting protein,Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5
6	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	58	Chemie (HOH)

Sequence modifications

D, I: 1 - 99 (UniProt: Q0VGL1)

PDB	External Database	Details
Met -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	111196.9
All*	Total formula weight	111196.9

*Water molecules are not included.