5Y16

Crystal structure of human DUSP28(Y102H)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dual specificity phosphatase 28	polymer	197	20576.5	2	UniProt (Q4G0W2) Pfam (PF00782)	Homo sapiens (Human)
2	C, E (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
3	D, F, G (A, B)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
4	H, I (A, B)	water	water		18.0	47	Chemie (HOH)

Sequence modifications

A, B: 1 - 176 (UniProt: Q4G0W2)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Gln 59	Arg 59	engineered mutation
His 102	Tyr 102	engineered mutation
Ser 103	Cys 103	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41152.9
Non-Polymers*	Number of molecules	5
	Total formula weight	296.3
All*	Total formula weight	41449.2

*Water molecules are not included.