5XY9

Structure of the MST4 and 14-3-3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	14-3-3 protein zeta/delta	polymer	267	30444.1	2	UniProt (P63104) Pfam (PF00244)	Homo sapiens (Human)	Protein kinase C inhibitor protein 1,KCIP-1
2	C, D (C, D)	Peptide from Serine/threonine-protein kinase 26	polymer	12	1539.5	2	UniProt (Q9P289)	Homo sapiens	MST3 and SOK1-related kinase,Mammalian STE20-like protein kinase 4,STE20-like kinase MST4,Serine/threonine-protein kinase MASK
3	E (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	F (A)	2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		354.4	1	Chemie (PE4)
5	G, H, I, J (A, B, C, D)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

A, B: 1 - 245 (UniProt: P63104)

PDB	External Database	Details
Met -21	-	expression tag
Ser -20	-	expression tag
Tyr -19	-	expression tag
Tyr -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Leu -11	-	expression tag
Glu -10	-	expression tag
Ser -9	-	expression tag
Thr -8	-	expression tag
Ser -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Lys -3	-	expression tag
Ala -2	-	expression tag
Gly -1	-	expression tag
Leu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63967.1
Non-Polymers*	Number of molecules	2
	Total formula weight	446.5
All*	Total formula weight	64413.6

*Water molecules are not included.