5XWT

Crystal structure of PTPdelta Ig1-Fn1 in complex with SALM5 LRR-Ig

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Receptor-type tyrosine-protein phosphatase delta	polymer	402	44089.6	2	UniProt (Q64487) Pfam (PF07679) Pfam (PF13927) Pfam (PF00041) In PDB	Mus musculus (Mouse)	R-PTP-delta
2	B, D	Leucine-rich repeat and fibronectin type-III domain-containing protein 5	polymer	367	41383.5	2	UniProt (Q96NI6) Pfam (PF13855) Pfam (PF07679) In PDB	Homo sapiens (Human)
3	E, F, H, I, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
4	G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		627.6	1	In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ)		triacetyl-beta-chitotriose
5	A, B, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

A, C: 27 - 417 (UniProt: Q64487)

PDB	External Database	Details
Leu 22	-	expression tag
Met 23	-	expression tag
Gly 24	-	expression tag
Cys 25	-	expression tag
Val 26	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
His 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag

B, D: 18 - 379 (UniProt: Q96NI6)

PDB	External Database	Details
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	170946.2
Branched	Number of molecules	6
	Total formula weight	2749.6
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	174580.6

*Water molecules are not included.