5XWD
Crystal structure of the complex of 059-152-Fv and EGFR-ECD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 651 | 71688.7 | 1 | UniProt (P00533) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) | Homo sapiens (Human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | B (H) | VH chain of 059-152 | polymer | 132 | 14017.6 | 1 | Homo sapiens | ||
| 3 | C (D) | VL chain of 059-152 | polymer | 120 | 12509.7 | 1 | Homo sapiens | ||
| 4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1317.2 | 1 | In PDB GlyTouCan (G39213VZ) | |||
| 5 | E, F, G, H, I... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 6 | AA, BA, CA, DA, EA... (H, D, A) | ZINC ION | non-polymer | 65.4 | 20 | Chemie (ZN) |
Sequence modifications
A: -23 - 619 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Gly 620 | - | expression tag |
| Ser 621 | - | expression tag |
| Glu 622 | - | expression tag |
| Asn 623 | - | expression tag |
| Leu 624 | - | expression tag |
| Tyr 625 | - | expression tag |
| Phe 626 | - | expression tag |
| Gln 627 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 98215.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1317.2 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2856.6 | |
| All* | Total formula weight | 102389.8 |
