5XVU
Crystal structure of the protein kinase CK2 catalytic domain from Plasmodium falciparum bound to ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Casein kinase 2, alpha subunit | polymer | 332 | 39705.0 | 3 | UniProt (Q8IIR9) Pfam (PF00069) | Plasmodium falciparum (isolate 3D7) | Casein kinase II,alpha subunit,putative |
| 2 | D, I, J, N, O (A, B, C) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | E, K, P (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | F, L, R (A, B, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
| 5 | G, H, M, S (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | Q (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | T, U, V (A, B, C) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A, B, C: 12 - 335 (UniProt: Q8IIR9)
| PDB | External Database | Details |
|---|---|---|
| Met 11 | - | expression tag |
| Ser 179 | Asp 179 | conflict |
| Ala 336 | - | expression tag |
| His 337 | - | expression tag |
| His 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
| His 341 | - | expression tag |
| His 342 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 119114.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2462.6 | |
| All* | Total formula weight | 121577.5 |
