5XVQ

Crystal structure of monkey Nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl Nicotinamide (MNA)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nicotinamide N-methyltransferase (NNMT)	polymer	284	31922.5	2	UniProt (F7ERX8) Pfam (PF01234)	Macaca mulatta (Rhesus macaque)	Uncharacterized protein
2	C, F (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3	D, G (A, B)	3-carbamoyl-1-methylpyridin-1-ium	non-polymer		137.2	2	Chemie (8GC)
4	E, H (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	I, J (A, B)	water	water		18.0	192	Chemie (HOH)

Sequence modifications

A, B: 1 - 264 (UniProt: F7ERX8)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63845.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1227.3
All*	Total formula weight	65072.3

*Water molecules are not included.