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5XUS

Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TTTA PAM)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
LbCpf1polymer1231144170.61Pfam (PF18501)
Pfam (PF21918)
Pfam (PF22222)
Pfam (PF18516)
Pfam (PF18510)
UniProt (by SIFTS) (A0A182DWE3)
Lachnospiraceae bacterium ND2006
2B
(B)
crRNApolymer4012879.61synthetic construct
3C
(C)
DNA (29-MER)polymer298872.71synthetic constructTarget DNA strand
4D
(D)
DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*A)-3')polymer92681.81synthetic constructNon-target DNA strand
5E, H
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6F, G
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
7I, J, K
(B)
SODIUM IONnon-polymer23.03Chemie (NA)
8L, M, N
(A, B, C)
waterwater18.0135Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight168604.8
Non-Polymers*Number of molecules7
Total formula weight241.7
All*Total formula weight168846.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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