5XSK

Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (D)	DNA (5'-D(P*TP*TP*CP*AP*AP*GP*AP*CP*CP*A)-3')	polymer	10	3013.0	1		Escherichia coli BL21
2	B (F)	DNA (5'-D(P*TP*GP*GP*TP*CP*TP*TP*GP*AP*A)-3')	polymer	10	3075.0	1		Escherichia coli BL21
3	C, D (A, B)	Hepatoma-derived growth factor	polymer	120	13735.5	2	UniProt (Q8VHK7) Pfam (PF00855)	Rattus norvegicus (Rat)	HDGF
4	E, F (A, B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)

Sequence modifications

A, B: 1 - 100 (UniProt: Q8VHK7)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	33559.0
Non-Polymers*	Number of molecules	2
	Total formula weight	236.3
All*	Total formula weight	33795.4

*Water molecules are not included.