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5XOW

Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'A7' on the target strand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
TtAgo (D546N)polymer68576727.81UniProt (Q746M7)
Pfam (PF22472)
Pfam (PF18309)
Pfam (PF22474)
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Uncharacterized protein
2B
(C)
DNA (5'-D(P*(TD)P*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3')polymer216588.31Thermus thermophilus
3C
(G)
RNA (5'-R(P*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*AP*CP*CP*UP*CP*G)-3')polymer206271.81Thermus thermophilus
4D
(C)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
A: 1 - 685 (UniProt: Q746M7)
PDBExternal DatabaseDetails
Asn 546Asp 546engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight89587.8
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight89612.1
*Water molecules are not included.

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PDB entries from 2025-12-17

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