5XOW
Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'A7' on the target strand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TtAgo (D546N) | polymer | 685 | 76727.8 | 1 | UniProt (Q746M7) Pfam (PF22472) Pfam (PF18309) Pfam (PF22474) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | Uncharacterized protein |
| 2 | B (C) | DNA (5'-D(P*(TD)P*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3') | polymer | 21 | 6588.3 | 1 | Thermus thermophilus | ||
| 3 | C (G) | RNA (5'-R(P*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*AP*CP*CP*UP*CP*G)-3') | polymer | 20 | 6271.8 | 1 | Thermus thermophilus | ||
| 4 | D (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 1 - 685 (UniProt: Q746M7)
| PDB | External Database | Details |
|---|---|---|
| Asn 546 | Asp 546 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 89587.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 89612.1 |






