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5XOW

Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'A7' on the target strand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
TtAgo (D546N)polymer68576727.81UniProt (Q746M7)Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Uncharacterized protein
2B
(C)
DNA (5'-D(P*(TD)P*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3')polymer216588.31Thermus thermophilus
3C
(G)
RNA (5'-R(P*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*AP*CP*CP*UP*CP*G)-3')polymer206271.81Thermus thermophilus
4D
(C)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
A: 1 - 685 (UniProt: Q746M7)
PDBExternal DatabaseDetails
Asn 546Asp 546engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight89587.8
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight89612.1
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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