5XN3
Crystal structure of SPSB2 in complex with a rational designed RGD containing cyclic peptide inhibitor of SPSB2-iNOS interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SPRY domain-containing SOCS box protein 2 | polymer | 209 | 22896.6 | 1 | UniProt (Q99619) Pfam (PF00622) | Homo sapiens (Human) | SSB-2,Gene-rich cluster protein C9 |
| 2 | B (B) | cR8 peptide from NOS2 | polymer | 8 | 901.9 | 1 | UniProt (by SIFTS) (P35228) BIRD (PRD_002275) | Homo sapiens | |
| 3 | C, D (A, B) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A: 22 - 220 (UniProt: Q99619)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | cloning artifact |
| Gly 21 | - | cloning artifact |
| Gly 221 | - | expression tag |
| Ser 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
| His 226 | - | expression tag |
| His 227 | - | expression tag |
| His 228 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23798.5 | |
| All* | Total formula weight | 23798.5 |
