5XMX
Co-crystal structure of Inhibitor compound in complex with human PPARdelta LBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor delta | polymer | 275 | 31430.5 | 2 | UniProt (Q03181) Pfam (PF00104) | Homo sapiens (Human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
| 2 | C, D (A, B) | (E)-6-[2-[[[4-(furan-2-yl)phenyl]carbonyl-methyl-amino]methyl]phenoxy]-4-methyl-hex-4-enoic acid | non-polymer | 433.5 | 2 | Chemie (89L) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A, B: 171 - 441 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| Gly 167 | - | expression tag |
| Ser 168 | - | expression tag |
| His 169 | - | expression tag |
| Met 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62861.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 867.0 | |
| All* | Total formula weight | 63728.1 |
