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5XMP

Plasmodium vivax SHMT(C346A) bound with PLP-glycine and MF057

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CSerine hydroxymethyltransferasepolymer44249217.13UniProt (A0A1G4H5I1)
Pfam (PF00464)
UniProt (by SIFTS) (A5K8L9)
In PDB
Plasmodium vivax
2A, B, CN-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]non-polymer306.23Chemie (PLG)
3A, B, C4-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]-~{N}-methyl-~{N}-[2,2,2-tris(fluoranyl)ethyl]benzenesulfonamidenon-polymer613.63Chemie (8A3)
4A, CCHLORIDE IONnon-polymer35.52Chemie (CL)
5waterwater18.0335Chemie (HOH)
Sequence modifications
A, B, C: 1 - 442 (UniProt: A0A1G4H5I1)
PDBExternal DatabaseDetails
Ala 364Cys 364engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight147651.3
Non-Polymers*Number of molecules8
Total formula weight2830.3
All*Total formula weight150481.6
*Water molecules are not included.

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PDB entries from 2024-07-17

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