5XJV
Two intermediate states of conformation switch in dual specificity phosphatase 13a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dual specificity protein phosphatase 13 isoform A | polymer | 185 | 20266.0 | 2 | UniProt (Q6B8I1) Pfam (PF00782) | Homo sapiens (Human) | DUSP13A,Branching-enzyme interacting DSP,Muscle-restricted DSP,MDSP |
| 2 | C, D (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 414 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 185 (UniProt: Q6B8I1)
| PDB | External Database | Details |
|---|---|---|
| Ala 18 | Cys 18 | engineered mutation |
| Ala 35 | Cys 35 | engineered mutation |
| Ala 77 | Cys 77 | engineered mutation |
| Ser 129 | Cys 129 | engineered mutation |
| Ala 176 | Cys 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40532.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 40722.0 |
