5XHC

Crystal structure of T2R-TTL-PO10 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Tubulin alpha chain	polymer	450	50041.3	2	UniProt (A0A0R4I993) Pfam (PF00091) Pfam (PF03953) In PDB	Sus barbatus (Bearded pig)
2	B, D	Tubulin beta chain	polymer	445	49999.9	2	UniProt (A0A0R4I995) Pfam (PF00091) Pfam (PF03953) In PDB	Sus barbatus (Bearded pig)
3	E	Stathmin-4	polymer	184	21637.7	1	UniProt (P63043) Pfam (PF00836) In PDB	Rattus norvegicus (Rat)	Stathmin-like protein B3,RB3
4	F	TUBULIN TYROSINE LIGASE	polymer	384	44378.5	1	UniProt (E1BQ43) In PDB	Gallus gallus (Chicken)
5	A, C, D	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	3	Chemie (GTP)
6	A, B, C	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
7	B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
8	B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
9	B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
10	B	(3Z,6Z)-3-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]-6-[[3-(4-fluorophenyl)carbonylphenyl]methylidene]piperazine-2,5-dione	non-polymer		458.5	1	Chemie (87U)
11	F	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
12		water	water		18.0	103	Chemie (HOH)

Sequence modifications

F: 1 - 378 (UniProt: E1BQ43)

PDB	External Database	Details
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	266098.5
Non-Polymers*	Number of molecules	15
	Total formula weight	3584.4
All*	Total formula weight	269682.9

*Water molecules are not included.