5XEQ

Crystal Structure of human MDGA1 and human neuroligin-2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Neuroligin-2	polymer	576	64101.1	1	UniProt (Q8NFZ4) Pfam (PF00135) In PDB	Homo sapiens (Human)
2	B	MAM domain-containing glycosylphosphatidylinositol anchor protein 1	polymer	319	35038.7	1	UniProt (Q8NFP4) Pfam (PF13927) In PDB	Homo sapiens (Human)	GPI and MAM protein,GPIM,Glycosylphosphatidylinositol-MAM,MAM domain-containing protein 3
3	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A: 42 - 611 (UniProt: Q8NFZ4)

PDB	External Database	Details
Ala 39	-	expression tag
Asp 40	-	expression tag
Pro 41	-	expression tag
Gln 98	Asn 98	engineered mutation
Val 612	-	expression tag
Pro 613	-	expression tag
Arg 614	-	expression tag

B: 19 - 330 (UniProt: Q8NFP4)

PDB	External Database	Details
Ala 16	-	expression tag
Asp 17	-	expression tag
Pro 18	-	expression tag
Leu 331	-	expression tag
Val 332	-	expression tag
Pro 333	-	expression tag
Arg 334	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	99139.8
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	100227.8

*Water molecules are not included.