5XEM
Crystal structure of a hydrogen sulfide-producing enzyme (Fn1220) from Fusobacterium nucleatum in complex with L-lanthionine-PLP Schiff base
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cysteine synthase | polymer | 310 | 33525.5 | 2 | UniProt (Q8RE94) Pfam (PF00291) | Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586 | |
| 2 | C, Q (A, B) | (2R)-2-azanyl-3-[(2R)-2-azanyl-3-oxidanyl-3-oxidanylidene-propyl]sulfanyl-propanoic acid | non-polymer | 208.2 | 2 | Chemie (85F) | |||
| 3 | D, P, R (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 3 | Chemie (PLP) | |||
| 4 | E, F, S (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | G, H, I, J, K... (A, B) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 6 | M, Y (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 7 | N (A) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 8 | Z (B) | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE | non-polymer | 178.2 | 1 | Chemie (PG5) | |||
| 9 | AA, BA (A, B) | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 306 (UniProt: Q8RE94)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67051.1 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2326.6 | |
| All* | Total formula weight | 69377.6 |
