5XE1

Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with INCB14943

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Indoleamine 2,3-dioxygenase 1	polymer	403	45384.2	2	UniProt (P14902) Pfam (PF01231) In PDB	Homo sapiens (Human)	IDO-1,Indoleamine-pyrrole 2,3-dioxygenase
2	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	A, B	4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboxamidine	non-polymer		271.6	2	Chemie (IUU)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	90768.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1776.2
All*	Total formula weight	92544.7

*Water molecules are not included.