5XDX
Bovine heart cytochrome c oxidase in the reduced state with pH 7.3 at 1.99 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, N (A, N) | Cytochrome c oxidase subunit 1 | polymer | 514 | 57093.9 | 2 | UniProt (P00396) Pfam (PF00115) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide I |
| 2 | B, O (B, O) | Cytochrome c oxidase subunit 2 | polymer | 227 | 26068.4 | 2 | UniProt (P68530) Pfam (PF02790) Pfam (PF00116) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide II |
| 3 | C, P (C, P) | Cytochrome c oxidase subunit 3 | polymer | 260 | 29826.4 | 2 | UniProt (P00415) Pfam (PF00510) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide III |
| 4 | D, Q (D, Q) | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | polymer | 147 | 17179.6 | 2 | UniProt (P00423) Pfam (PF02936) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit IV isoform 1,COX IV-1 |
| 5 | E, R (E, R) | Cytochrome c oxidase subunit 5A, mitochondrial | polymer | 109 | 12453.1 | 2 | UniProt (P00426) Pfam (PF02284) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide Va |
| 6 | F, S (F, S) | Cytochrome c oxidase subunit 5B, mitochondrial | polymer | 94 | 10233.5 | 2 | UniProt (P00428) Pfam (PF01215) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide VIa,Cytochrome c oxidase polypeptide Vb,Cytochrome c oxidase subunit 6C |
| 7 | G, T (G, T) | Cytochrome c oxidase subunit 6A2, mitochondrial | polymer | 85 | 9629.8 | 2 | UniProt (P07471) Pfam (PF02046) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide VIa-heart,COXVIAH,Cytochrome c oxidase polypeptide VIb |
| 8 | H, U (H, U) | Cytochrome c oxidase subunit 6B1 | polymer | 85 | 10039.2 | 2 | UniProt (P00429) Pfam (PF02297) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide VII,Cytochrome c oxidase subunit AED,Cytochrome c oxidase subunit VIb isoform 1,COX VIb-1 |
| 9 | I, V (I, V) | Cytochrome c oxidase polypeptide VIc | polymer | 73 | 8537.0 | 2 | UniProt (P04038) Pfam (PF02937) | Bos taurus (Bovine) | Cytochrome c oxidase subunit STA,Cytochrome c oxidase subunit 6C |
| 10 | J, W (J, W) | Cytochrome c oxidase subunit VIIa-heart | polymer | 59 | 6682.7 | 2 | UniProt (P07470) Pfam (PF02238) | Bos taurus (Bovine) | Cytochrome c oxidase subunit VIIIc,VIIIC,Cytochrome c oxidase subunit VIIa-H,Cytochrome c oxidase subunit VIIa-muscle,Cytochrome c oxidase subunit VIIa-M,Cytochrome c oxidase subunit 7A1, mitochondrial |
| 11 | K, X (K, X) | Cytochrome c oxidase subunit VIIb | polymer | 56 | 6365.2 | 2 | UniProt (P13183) Pfam (PF05392) | Bos taurus (Bovine) | IHQ,Cytochrome c oxidase subunit 7B, mitochondrial |
| 12 | L, Y (L, Y) | Cytochrome c oxidase subunit VIIc | polymer | 47 | 5449.4 | 2 | UniProt (P00430) Pfam (PF02935) | Bos taurus (Bovine) | Cytochrome c oxidase polypeptide VIIIA,Cytochrome c oxidase subunit 7C, mitochondrial |
| 13 | M, Z (M, Z) | Cytochrome c oxidase subunit VIII-heart | polymer | 46 | 4967.8 | 2 | UniProt (P10175) Pfam (PF02285) | Bos taurus (Bovine) | Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8H,IX,VIIIb,Cytochrome c oxidase subunit 8B, mitochondrial |
| 14 | AA, BA, VB, WB (A, N) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 15 | CA, XB (A, N) | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) PubChem (27099) | |||
| 16 | DA, YB (A, N) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 17 | EA, RC, UA, ZB (A, P, C, N) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) PubChem (923) | |||
| 18 | FA, GB, JD, NC, SB... (A, D, Y, O, L...) | TRISTEAROYLGLYCEROL | non-polymer | 891.5 | 6 | Chemie (TGL) PubChem (11146) | |||
| 19 | AC, BC, GA, SC, TB... (N, A, P, M, C) | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 8 | Chemie (PGV) PubChem (21158857) PubChem (73746220) PubChem (5289145) PubChem (162368821) PubChem (163029036) | |||
| 20 | AD, BB, CB, CC, CD... (R, C, N, S, A...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 33 | Chemie (EDO) | |||
| 21 | OC, QA (O, B) | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) | |||
| 22 | AB, ID, MC, QC, RA... (C, W, O, P, B...) | CHOLIC ACID | non-polymer | 408.6 | 8 | Chemie (CHD) PubChem (16401672) PubChem (16758100) PubChem (18528842) PubChem (20638765) PubChem (303) PubChem (23636694) PubChem (23640631) PubChem (6676) PubChem (23876184) PubChem (24836753) PubChem (24883735) PubChem (43835083) PubChem (16401251) PubChem (44135469) PubChem (44629918) PubChem (44657327) PubChem (21139644) PubChem (45114537) PubChem (45382168) PubChem (122340) PubChem (1762378) PubChem (46397523) PubChem (46783697) PubChem (49791911) PubChem (49796810) PubChem (50989873) PubChem (51432410) PubChem (51546373) PubChem (53298695) PubChem (53393606) PubChem (53477699) PubChem (160636) PubChem (221493) PubChem (57937243) PubChem (44339334) PubChem (58133002) PubChem (58582306) PubChem (376829) PubChem (439520) PubChem (58984417) PubChem (59032051) PubChem (59316662) PubChem (59877711) PubChem (59963674) PubChem (59997751) PubChem (60076012) PubChem (60098994) PubChem (60114995) PubChem (440427) PubChem (46780112) PubChem (66678354) PubChem (68097396) PubChem (68131418) PubChem (68318251) PubChem (68338620) PubChem (68372213) PubChem (71260265) PubChem (70649328) PubChem (70824975) PubChem (70930320) PubChem (70930789) PubChem (70960845) PubChem (637625) PubChem (59130005) PubChem (59381614) PubChem (59903914) PubChem (67122255) PubChem (3246132) PubChem (69904012) PubChem (130213) PubChem (145883) PubChem (70866085) PubChem (71001249) PubChem (239672) PubChem (71314856) PubChem (71752895) PubChem (5283869) PubChem (5283870) PubChem (5283871) PubChem (5283873) PubChem (5283875) PubChem (5283877) PubChem (5283878) PubChem (74765127) PubChem (89830646) PubChem (5302608) PubChem (5315844) PubChem (91128541) PubChem (91810856) PubChem (5283876) PubChem (5283879) PubChem (5283880) PubChem (5283872) PubChem (5283874) PubChem (98044963) PubChem (99565617) PubChem (122645815) PubChem (124161889) PubChem (124318072) PubChem (124488681) PubChem (125037036) PubChem (126577457) PubChem (129274856) PubChem (129274855) PubChem (129359810) PubChem (6708709) PubChem (6850901) PubChem (6850905) PubChem (99564899) PubChem (99565857) PubChem (133135020) PubChem (133126746) PubChem (11350342) PubChem (117684834) PubChem (117767695) PubChem (117944573) PubChem (118241311) PubChem (9802771) PubChem (121232934) PubChem (9846429) PubChem (9866174) PubChem (122537896) PubChem (122537897) PubChem (122644681) PubChem (122644923) PubChem (122646384) PubChem (12303168) PubChem (13020196) PubChem (71172094) PubChem (124328806) PubChem (124364505) PubChem (124425250) PubChem (124488680) PubChem (124511215) PubChem (124518077) PubChem (124518078) PubChem (124518446) PubChem (124761950) PubChem (12080557) PubChem (12303167) PubChem (12303172) PubChem (12303175) PubChem (12303178) PubChem (12303180) PubChem (13020205) PubChem (124841930) PubChem (124896923) PubChem (124896924) PubChem (124896925) PubChem (124896926) PubChem (124904187) PubChem (124904188) PubChem (124906682) PubChem (124906683) PubChem (124914603) PubChem (124914604) PubChem (124914605) PubChem (124914606) PubChem (125027431) PubChem (125037037) PubChem (162771689) PubChem (163059393) PubChem (163059399) PubChem (163059389) PubChem (126422551) PubChem (126422552) PubChem (126577461) PubChem (126672319) PubChem (166858402) PubChem (126969154) PubChem (129106816) PubChem (129460958) PubChem (129600748) PubChem (129628082) PubChem (130220803) PubChem (131700165) PubChem (132441695) PubChem (133548348) PubChem (133612061) PubChem (133655733) PubChem (133687870) PubChem (133688934) PubChem (134462403) PubChem (134555902) PubChem (134866321) PubChem (135373095) PubChem (137474142) PubChem (138107312) PubChem (139248576) PubChem (139291795) PubChem (139372812) PubChem (140618124) PubChem (141854542) PubChem (142134118) PubChem (143658950) PubChem (144316980) PubChem (145264188) PubChem (145714625) PubChem (146030145) PubChem (146665897) PubChem (154033190) PubChem (154036252) PubChem (154747009) PubChem (154825357) PubChem (155275443) PubChem (155605940) PubChem (157048615) PubChem (157269375) PubChem (157351909) PubChem (157383333) PubChem (158041002) PubChem (158420924) PubChem (158675416) PubChem (160081178) PubChem (160743345) PubChem (160917187) PubChem (161973449) PubChem (163059390) PubChem (163059391) PubChem (163059392) PubChem (163059394) PubChem (163059395) PubChem (163059396) PubChem (163059397) PubChem (163059398) PubChem (163059400) PubChem (163452349) PubChem (163452350) PubChem (163452351) PubChem (167344826) PubChem (168841979) PubChem (168841990) PubChem (168845540) PubChem (169410142) PubChem (169436432) PubChem (171721516) PubChem (157060709) | |||
| 23 | ED, FD, GD, QB, VA... (T, G, C) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE | non-polymer | 768.1 | 6 | Chemie (PEK) PubChem (21158855) PubChem (44552596) PubChem (45253969) PubChem (45253978) PubChem (53301835) PubChem (72280040) PubChem (53652586) PubChem (73659094) PubChem (5289133) PubChem (123132887) PubChem (9546819) PubChem (6426736) PubChem (134812608) PubChem (9546829) PubChem (9546830) PubChem (145998242) PubChem (156613384) PubChem (162679672) | |||
| 24 | HD, PB, UC, ZA (T, G, P, C) | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 25 | EB, FB, KD, UB, XC... (C, Z, M, P) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 6 | Chemie (DMU) PubChem (24776995) PubChem (16396531) PubChem (45253991) PubChem (45254001) PubChem (24802064) PubChem (56845266) PubChem (58112552) PubChem (45253971) PubChem (59518661) PubChem (49866911) PubChem (70796430) PubChem (70839938) PubChem (71307274) PubChem (3637526) PubChem (5288091) PubChem (95370473) PubChem (98046563) PubChem (5288728) PubChem (101207920) PubChem (126735852) PubChem (95370474) PubChem (95370475) PubChem (95370476) PubChem (98046559) PubChem (98046561) PubChem (100941450) PubChem (100950626) PubChem (102219024) PubChem (118704896) PubChem (123134571) PubChem (124867949) PubChem (124867950) PubChem (124867951) PubChem (124867952) PubChem (126731012) PubChem (126731036) PubChem (126735974) PubChem (168490163) | |||
| 26 | JB, PC (E, O) | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE | non-polymer | 759.1 | 2 | Chemie (PSC) PubChem (122219) PubChem (46936343) PubChem (53962049) PubChem (446962) PubChem (5313189) PubChem (5313191) PubChem (5289212) PubChem (5313188) PubChem (5313190) PubChem (124586127) | |||
| 27 | BD, LB (S, F) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 28 | AE, BE, CE, DE, EE... (P, Q, R, S, T...) | water | water | 18.0 | 1941 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 409052.2 | |
| Non-Polymers* | Number of molecules | 89 |
| Total formula weight | 35599.8 | |
| All* | Total formula weight | 444651.9 |
