5XAG

Crystal structure of tubulin-stathmin-TTL-Compound Z2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (P81947) Pfam (PF00091) Pfam (PF03953)	Bos taurus (Bovine)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2	B, D (B, D)	Tubulin beta-2B chain	polymer	445	49999.9	2	UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953)	Bos taurus (Bovine)
3	E (E)	Stathmin-4	polymer	189	22125.3	1	UniProt (P63043) Pfam (PF00836)	Rattus norvegicus (Rat)	Stathmin-like protein B3,RB3
4	F (F)	Tubulin tyrosine ligase	polymer	378	43549.6	1	UniProt (E1BQ43)	Gallus gallus (Chicken)
5	G, V (A, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	EA, H, JA, N, W (D, A, F, B, C)	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
7	FA, GA, I, J, L... (D, A, B, C)	GLYCEROL	non-polymer		92.1	12	Chemie (GOL)
8	AA, K, R (C, A, B)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
9	DA, M (D, B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
10	S (B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
11	HA, T (D, B)	(3~{R},4~{R})-3-(hydroxymethyl)-4-(4-methoxy-3-oxidanyl-phenyl)-1-(3,4,5-trimethoxyphenyl)azetidin-2-one	non-polymer		389.4	2	Chemie (93X)
12	BA, CA, IA (C, E)	IMIDAZOLE	non-polymer		69.1	3	Chemie (IMD)
13	KA (F)	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
14	LA, MA, NA, OA, PA... (A, B, C, D, E...)	water	water		18.0	130	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	266083.6
Non-Polymers*	Number of molecules	31
	Total formula weight	4966.1
All*	Total formula weight	271049.7

*Water molecules are not included.