5X8M
PD-L1 in complex with durvalumab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Programmed cell death 1 ligand 1 | polymer | 123 | 14224.2 | 1 | UniProt (Q9NZQ7) Pfam (PF07686) | Homo sapiens (Human) | Programmed death ligand 1,B7 homolog 1,B7-H1 |
| 2 | B (B) | durvalumab heavy chain | polymer | 235 | 25404.4 | 1 | Homo sapiens | ||
| 3 | C (C) | durvalumab light chain | polymer | 215 | 23601.2 | 1 | Homo sapiens | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A: 18 - 134 (UniProt: Q9NZQ7)
| PDB | External Database | Details |
|---|---|---|
| Glu 47 | Gln 47 | engineered mutation |
| His 135 | - | expression tag |
| His 136 | - | expression tag |
| His 137 | - | expression tag |
| His 138 | - | expression tag |
| His 139 | - | expression tag |
| His 140 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63229.8 | |
| All* | Total formula weight | 63229.8 |
