5X33

Leukotriene B4 receptor BLT1 in complex with BIIL260

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	LTB4 receptor,Lysozyme,LTB4 receptor	polymer	523	57755.1	1	UniProt (Q9WTK1) UniProt (A0A097J792) Pfam (PF00001) Pfam (PF00959) In PDB	Cavia porcellus (Guinea pig)	Leukotriene B4 receptor
2	A	4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamide	non-polymer		466.6	1	Chemie (7Y9)

Sequence modifications

A: 15 - 213 (UniProt: Q9WTK1)

PDB	External Database	Details
Glu 2	-	expression tag
Leu 3	-	expression tag
Met 4	-	expression tag
Asp 5	-	expression tag
Tyr 6	-	expression tag
Lys 7	-	expression tag
Asp 8	-	expression tag
Asp 9	-	expression tag
Asp 10	-	expression tag
Asp 11	-	expression tag
Lys 12	-	expression tag
Glu 13	-	expression tag
Phe 14	-	expression tag
Gly 83	His 83	engineered mutation
Gly 88	Lys 88	engineered mutation
Ala 212	Val 212	engineered mutation

A: 1002 - 1161 (UniProt: A0A097J792)

PDB	External Database	Details
Thr 1054	Cys 54	engineered mutation
Ala 1097	Cys 97	engineered mutation
Gly 1200	-	linker
Ser 1201	-	linker
Gly 1202	-	linker
Ser 1203	-	linker

A: 214 - 348 (UniProt: Q9WTK1)

PDB	External Database	Details
Gly 900	-	linker
Ser 901	-	linker
Gly 902	-	linker
Ser 903	-	linker
Ala 309	Ser 309	engineered mutation
Glu 349	-	expression tag
Phe 350	-	expression tag
Leu 351	-	expression tag
Glu 352	-	expression tag
Val 353	-	expression tag
Leu 354	-	expression tag
Phe 355	-	expression tag
Gln 356	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57755.1
Non-Polymers*	Number of molecules	1
	Total formula weight	466.6
All*	Total formula weight	58221.7

*Water molecules are not included.