5X2Q
Crystal structure of the medaka fish taste receptor T1r2a-T1r3 ligand binding domains in complex with glycine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Taste receptor, type 1, member 2a | polymer | 461 | 51471.1 | 2 | UniProt (A0A173M0G2) Pfam (PF01094) | Oryzias latipes (Japanese rice fish) | T1r2a |
| 2 | B, D (B, D) | Taste receptor, type 1, member 3 | polymer | 478 | 53132.0 | 2 | UniProt (A0A173M094) Pfam (PF01094) | Oryzias latipes (Japanese rice fish) | T1r3 |
| 3 | E, G (H, J) | Fab16A Heavy chain | polymer | 225 | 24182.2 | 2 | Mus musculus (Mouse) | ||
| 4 | F, H (L, K) | Fab16A Light chain | polymer | 217 | 23899.2 | 2 | Mus musculus (Mouse) | ||
| 5 | I (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | J (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | BA, CA, DA, EA, FA... (C, A, D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) | |||
| 8 | HA, OA, R, Z (C, D, A, B) | GLYCINE | non-polymer | 75.1 | 4 | Chemie (GLY) | |||
| 9 | IA, KA, PA, S, T (C, D, A) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 10 | AA, JA, QA (B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 11 | RA (K) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 12 | SA, TA, UA, VA, WA... (A, B, C, D, H...) | water | water | 18.0 | 407 | Chemie (HOH) |
Sequence modifications
A, C: 20 - 474 (UniProt: A0A173M0G2)
B, D: 20 - 491 (UniProt: A0A173M094)
| PDB | External Database | Details |
|---|---|---|
| Ser 475 | - | expression tag |
| Gly 476 | - | expression tag |
| Ile 477 | - | expression tag |
| Glu 478 | - | expression tag |
| Gly 479 | - | expression tag |
| Arg 480 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 492 | - | expression tag |
| Gly 493 | - | expression tag |
| Ile 494 | - | expression tag |
| Glu 495 | - | expression tag |
| Gly 496 | - | expression tag |
| Arg 497 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 305369.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 5207.0 | |
| All* | Total formula weight | 311587.0 |
